2009
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for Coco Chanel
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for Coco Chanel
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for Coco Chanel

2006
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for In Her Shoes

2003
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for Hell on Heels: The Battle of Mary Kay

1995
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Guarding Tess

1993
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Used People

1991
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Postcards From the Edge
• British Academy of Film & Television Arts, Actress in a Leading Role for Postcards From the Edge
• British Academy of Film & Television Arts, Actress in a Supporting Role for Steel Magnolias

1989
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Madame Sousatzka

1988
• Golden Globe, Best Performance by an Actress in a Miniseries or Motion Picture Made for Television for Out on a Limb

1984
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Terms of Endearment
• British Academy of Film & Television Arts, Actress for Terms of Endearment
• Academy Award, Actress in a Leading Role for Terms of Endearment

1980
• British Academy of Film & Television Arts, Actress for Being There
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Being There

1978
• Academy Award, Actress in a Leading Role for The Turning Point

1970
• Golden Globe, Actress in a Leading Role - Musical or Comedy for Sweet Charity

1968
• Golden Globe, Actress in a Leading Role - Musical or Comedy for Woman Times Seven

1967
• Golden Globe, Actress in a Leading Role - Musical or Comedy for Gambit

1965
• British Academy of Film & Television Arts, Foreign Actress for What a Way to Go!
• British Academy of Film & Television Arts, Foreign Actress for Irma La Douce

1964
• Golden Globe, Actress in a Leading Role - Musical or Comedy for Irma La Douce
• Academy Award, Actress for Irma La Douce

1962
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for The Children's Hour

1961
• Golden Globe, Actress in a Leading Role - Musical or Comedy for The Apartment
• British Academy of Film & Television Arts, Foreign Actress for The Apartment
• Academy Award, Actress for The Apartment

1960
• British Academy of Film & Television Arts, Foreign Actress for Ask Any Girl
• Golden Globe, Actress in a Leading Role - Musical or Comedy for Ask Any Girl

1959
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Some Came Running
• Academy Award, Actress for Some Came Running

1957
• British Academy of Film & Television Arts, Foreign Actress for The Trouble With Harry