2023
• Los Premios Goya, Best Supporting Actress for En los márgenes

2022
• Academy Award, Actress in a Leading Role for Madres paralelas
• Premios Feroz, Best Main Actress in a Film for Madres paralelas
• Los Premios Goya, Best Leading Actress for Madres paralelas

2020
• Los Premios Goya, Best Leading Actress for Dolor y gloria

2019
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for The Assassination of Gianni Versace: American Crime Story
• Los Premios Goya, Best Leading Actress for Todos lo saben
• Golden Globe, Best Performance by an Actress in a Supporting Role in a Series, Limited Series or Motion Picture Made for Television for The Assassination of Gianni Versace: American Crime Story

2018
• Emmy (Primetime), Outstanding Supporting Actress in a Limited Series or Movie for The Assassination of Gianni Versace: American Crime Story
• Los Premios Goya, Best Leading Actress for Loving Pablo

2017
• Los Premios Goya, Best Leading Actress for La reina de España

2016
• Los Premios Goya, Best Leading Actress for Ma ma

2013
• Los Premios Goya, Best Leading Actress for Twice Born

2010
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Nine
• Los Premios Goya, Best Leading Actress for Los abrazos rotos
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Nine
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for Nine
• Academy Award, Actress in a Supporting Role for Nine

2009
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Vicky Cristina Barcelona
• Academy Award, Actress in a Supporting Role for Vicky Cristina Barcelona
• Los Premios Goya, Best Supporting Actress for Vicky Cristina Barcelona
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Vicky Cristina Barcelona
• British Academy of Film & Television Arts, Supporting Actress for Vicky Cristina Barcelona

2007
• Los Premios Goya, Best Leading Actress for Volver
• British Academy of Film & Television Arts, Actress in a Leading Role for Volver
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Volver
• Academy Award, Actress in a Leading Role for Volver
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Volver

2006
• Cannes Film Festival, Best Actress for Volver

2005
• Los Premios Goya, Best Leading Actress for Non ti muovere

1999
• Los Premios Goya, Best Leading Actress for La niña de tus ojos

1993
• Los Premios Goya, Best Leading Actress for Jamón, jamón