2022
• Golden Globe, Best Performance by an Actress, Limited Series, Anthology Series or a Motion Picture Made for Television for Mare of Easttown
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Limited Series for Mare of Easttown
• British Academy of Film & Television Arts, Leading Actress for Mare of Easttown

2021
• Emmy (Primetime), Outstanding Lead Actress in a Limited or Anthology Series or Movie for Mare of Easttown

2016
• Academy Award, Actress in a Supporting Role for Steve Jobs
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Steve Jobs
• British Academy of Film & Television Arts, Supporting Actress for Steve Jobs
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Steve Jobs

2015
• Australian Academy of Cinema and Television Arts Awards, Best Lead Actress for The Dressmaker

2014
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Labor Day

2012
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for Mildred Pierce
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Carnage
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for Mildred Pierce

2011
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for Mildred Pierce

2009
• British Academy of Film & Television Arts, Leading Actress for The Reader
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for The Reader
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for The Reader
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Revolutionary Road
• British Academy of Film & Television Arts, Leading Actress for Revolutionary Road
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Revolutionary Road
• Academy Award, Actress in a Leading Role for The Reader

2007
• Academy Award, Actress in a Leading Role for Little Children
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Little Children
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Little Children
• British Academy of Film & Television Arts, Actress in a Leading Role for Little Children

2005
• Academy Award, Actress in a Leading Role for Eternal Sunshine of the Spotless Mind
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for Finding Neverland
• British Academy of Film & Television Arts, Actress in a Leading Role for Finding Neverland
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Eternal Sunshine of the Spotless Mind
• British Academy of Film & Television Arts, Actress in a Leading Role for Eternal Sunshine of the Spotless Mind
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Eternal Sunshine of the Spotless Mind

2002
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Iris
• British Academy of Film & Television Arts, Actress in a Supporting Role for Iris
• Academy Award, Actress in a Supporting Role for Iris

2001
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Quills

1998
• Academy Award, Actress in a Leading Role for Titanic
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Titanic
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Titanic

1996
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Sense and Sensibility
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Sense and Sensibility
• Academy Award, Actress in a Supporting Role for Sense and Sensibility
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for Sense and Sensibility
• British Academy of Film & Television Arts, Actress in a Supporting Role for Sense and Sensibility