2016
• Emmy (Primetime), Outstanding Supporting Actor in a Drama Series for Ray Donovan

2015
• Golden Globe, Best Performance by an Actor in a Supporting Role in a Series, Limited Series or Motion Picture Made for Television for Ray Donovan

2014
• Emmy (Primetime), Outstanding Supporting Actor in a Drama Series for Ray Donovan
• Golden Globe, Best Performance by an Actor in a Supporting Role in a Series, Limited Series or Motion Picture Made for Television for Ray Donovan

2006
• Emmy (Primetime), Outstanding Lead Actor in a Miniseries or a Movie for Pope John Paul II

2005
• Screen Actors Guild Awards, Outstanding Performance by a Male Actor in a Television Movie or Miniseries for Mitch Albom's The Five People You Meet in Heaven

2002
• Emmy (Primetime), Outstanding Supporting Actor in a Miniseries or a Movie for Uprising
• Golden Globe, Best Performance By an Actor in a Supporting Role in a Motion Picture for Ali

2001
• Academy Award, Actor in a Supporting Role for Ali

1998
• Golden Globe, Best Performance By an Actor in a Supporting Role in a Motion Picture for John Grisham's The Rainmaker

1993
• Golden Globe, Best Performance by an Actor in a Miniseries or Motion Picture Made for Television for The Last of His Tribe

1986
• Golden Globe, Best Performance By an Actor in a Motion Picture - Drama for Runaway Train

1985
• Academy Award, Actor in a Leading Role for Runaway Train

1980
• Golden Globe, Best Performance By an Actor in a Motion Picture - Drama for The Champ

1979
• Golden Globe, Best Performance By an Actor in a Motion Picture - Drama for Coming Home

1978
• Academy Award, Actor in a Leading Role for Coming Home

1973
• Golden Globe, Best Performance By an Actor in a Motion Picture - Drama for Deliverance

1970
• British Academy of Film & Television Arts, Most Promising Newcomer to Leading Film Roles for Midnight Cowboy
• Golden Globe, Best Performance By an Actor in a Motion Picture - Drama for Midnight Cowboy

1969
• Academy Award, Actor for Midnight Cowboy