2018
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for The Big Sick
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for The Big Sick

2014
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for Top of the Lake

2010
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Drama Series for Saving Grace

2009
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Drama Series for Saving Grace
• Emmy (Primetime), Outstanding Lead Actress in a Drama Series for Saving Grace

2008
• Golden Globe, Best Performance by an Actress in a Television Series - Drama for Saving Grace
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Drama Series for Saving Grace
• Emmy (Primetime), Outstanding Lead Actress in a Drama Series for Saving Grace

2004
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Thirteen
• British Academy of Film & Television Arts, Actress in a Supporting Role for Thirteen
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Thirteen
• Academy Award, Actress in a Supporting Role for Thirteen

2001
• Emmy (Primetime), Outstanding Supporting Actress in a Limited Series or Movie for Things You Can Tell Just by Looking at Her
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for When Billie Beat Bobby
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for Harlan County War

2000
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for Harlan County War

1994
• Golden Globe, Best Performance by an Actress in a Miniseries or Motion Picture Made for Television for The Positively True Adventures of the Alleged Texas Cheerleader-Murdering Mom
• Academy Award, Actress in a Leading Role for The Piano
• British Academy of Film & Television Arts, Actress in a Leading Role for The Piano
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for The Piano
• Academy Award, Actress in a Supporting Role for The Firm
• British Academy of Film & Television Arts, Actress in a Supporting Role for The Firm

1993
• Cannes Film Festival, Best Actress for The Piano
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for The Positively True Adventures of the Alleged Texas Cheerleader-Murdering Mom

1990
• Golden Globe, Best Performance by an Actress in a Miniseries or Motion Picture Made for Television for Roe vs. Wade

1989
• Emmy (Primetime), Outstanding Lead Actress for a Miniseries or Special for Roe vs. Wade

1988
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Broadcast News
• Academy Award, Actress in a Leading Role for Broadcast News