2020
• Screen Actors Guild Awards, Outstanding Performance by an Ensemble in a Drama Series for Big Little Lies
• Academy Award, Actress in a Supporting Role for Marriage Story
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Marriage Story
• Golden Globe, Best Actress in a Supporting Role in Any Motion Picture for Marriage Story
• Emmy (Primetime), Outstanding Supporting Actress in a Drama Series for Big Little Lies
• British Academy of Film & Television Arts, Supporting Actress for Marriage Story

2019
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for The Tale

2018
• Emmy (Primetime), Outstanding Lead Actress in a Limited Series or Movie for The Tale
• Golden Globe, Best Performance by an Actress in a Supporting Role in a Series, Limited Series or Motion Picture Made for Television for Big Little Lies
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Limited Series for Big Little Lies

2017
• Emmy (Primetime), Outstanding Supporting Actress in a Limited Series or Movie for Big Little Lies

2015
• Academy Award, Actress in a Supporting Role for Wild

2013
• Emmy (Primetime), Outstanding Lead Actress in a Comedy Series for Enlightened

2012
• Golden Globe, Best Performance by an Actress in a Television Series - Musical or Comedy for Enlightened

2009
• Golden Globe, Best Performance by an Actress in a Supporting Role in a Series, Limited Series or Motion Picture Made for Television for Recount
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for Recount

2008
• Emmy (Primetime), Outstanding Supporting Actress in a Miniseries or a Movie for Recount

1999
• Golden Globe, Best Performance by an Actress in a Miniseries or Motion Picture Made for Television for The Baby Dance

1993
• Golden Globe, Best Performance by an Actress in a Miniseries or Motion Picture Made for Television for Afterburn

1992
• Academy Award, Actress in a Leading Role for Rambling Rose
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Rambling Rose
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for Afterburn