College Football
Clemson at Louisville (2025)

The No. 20 Cardinals (7-2, 4-2 ACC) try to make it two straight over the Tigers (4-5, 3-4). Clemson leads the series 8-1 after Louisville prevailed 33-21 in 2024. The Cardinals' backfield of Browns, Isaac and Keyjuan, have combined for 11 touchdowns.