2022
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Being the Ricardos
• Academy Award, Actress in a Leading Role for Being the Ricardos
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Being the Ricardos

2021
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Limited Series for The Undoing
• Golden Globe, Best Actress - Television Motion Picture for The Undoing

2020
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for Bombshell
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Bombshell
• Golden Globe, Best Performance by an Actress in a Television Series - Drama for Big Little Lies
• Screen Actors Guild Awards, Outstanding Performance by an Ensemble in a Drama Series for Big Little Lies

2019
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Destroyer

2018
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Limited Series for Big Little Lies
• Australian Academy of Cinema and Television Arts Awards, Best Supporting Actress for Boy Erased
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for Big Little Lies

2017
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for Lion
• Academy Award, Actress in a Supporting Role for Lion
• British Academy of Film & Television Arts, Supporting Actress for Lion
• Emmy (Primetime), Outstanding Lead Actress in a Limited Series or Movie for Big Little Lies
• Australian Academy of Cinema and Television Arts Awards, Best Supporting Actress for Lion
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Lion

2016
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for Grace of Monaco

2013
• Golden Globe, Best Performance by an Actress in a Limited Series or Motion Picture Made for Television for Hemingway & Gellhorn
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for The Paperboy
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Supporting Role for The Paperboy
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Television Movie or Miniseries for Hemingway & Gellhorn

2012
• Emmy (Primetime), Outstanding Lead Actress in a Miniseries or Movie for Hemingway & Gellhorn

2011
• Academy Award, Actress in a Leading Role for Rabbit Hole
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Rabbit Hole
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for Rabbit Hole

2010
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for Nine

2005
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Birth

2004
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for Cold Mountain

2003
• Internationale Filmfestspiele Berlin, Silver Bear for Best Actress for The Hours
• Academy Award, Actress in a Leading Role for The Hours
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for The Hours
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for The Hours
• British Academy of Film & Television Arts, Actress in a Leading Role for The Hours
• Screen Actors Guild Awards, Outstanding Performance by a Female Actor in a Leading Role for The Hours

2002
• Golden Globe, Best Performance By an Actress in a Motion Picture - Drama for The Others
• Los Premios Goya, Best Leading Actress for The Others
• British Academy of Film & Television Arts, Actress in a Leading Role for The Others
• Academy Award, Actress in a Leading Role for Moulin Rouge
• Screen Actors Guild Awards, Outstanding Performance by a Cast in a Motion Picture for Moulin Rouge
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for Moulin Rouge

1996
• Golden Globe, Best Performance By an Actress in a Motion Picture - Musical or Comedy for To Die For
• British Academy of Film & Television Arts, Actress in a Leading Role for To Die For

1992
• Golden Globe, Best Performance By an Actress in a Supporting Role in a Motion Picture for Billy Bathgate