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Dean comes to a stunning decision that will alter his life -- as well as Sam's; Rowena and Crowley face off, putting Castiel in the middle.

Supernatural

Brother's Keeper

Dean takes matters into his own hands regarding Stynes; Sam attempts to come to terms with his decision.

The Prisoner

While investigating a strange murder, Sam and Dean discover the killer has the same tattoo as those from the Styne family; Castiel plays referee when Charlie and Rowena must work together; Crowley turns to an old enemy for help with Rowena.

Dark Dynasty

Castiel asks Sam and Dean to help Claire find her mother, but when they learn what took the woman, they suspect a happy ending is impossible.

Angel Heart

Sam looks for a magical box built by former Men of Letters, Magnus, hoping it will cure Dean, but is surprised by a deadly alarm system.

The Werther Project

Charlie contacts Sam and Dean after she finds the book of the dead -- which could help eliminate the mark of Cain; Castiel and Metatron look for Castiel's grace.

Book of the Damned

Castiel and Sam pursue a lead about the Mark of Cain; Rowena (Ruth Connell) and Dean have an encounter.

Inside Man

Dean and Sam investigate grisly, identical suicides committed by various people with little in common; the brothers begin to suspect that a priest is involved.

Paint It Black

Sam ignores Dean's directive and continues to search for a cure; a new murder case brings the brothers in contact with Cole -- who ends up being infected by a Khan worm that turns men into murderers.

The Things They Carried

Sam, Dean and Castiel must deal with Cain's (Timothy Omundson) return; Rowena and Crowley grow closer.

The Executioner's Song

Dean and Sam race to stop a vengeful ghost who has been killing people through various electronic devices.

Halt & Catch Fire

Sam and Dean tackle a case where people vanish into thin air, leaving only their clothes behind; Dean becomes a victim.

About a Boy

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S10 E22 | The Prisoner