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Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Dr. Pimple Popper

Popping Popeye

Patrick's nose is covered by huge bumps, and he can barely breathe; Aziza and Lauren are friends who bonded over their matching wrist lumps; Joe has a mound in the middle of his forehead that looks like a third eye.

Every Rosacea Has Its Thorn

Amber has hundreds of tumors on her face; Antonio has a mound on his spine and is afraid it might be impossible to remove; sisters Cheri and Janice both suffer from possibly matching lumps; Tatiana has an embarrassing bump on her butt cheek.

Sisters Lumpity Lump Lump

Louis is a veteran who is covered in scaly, dry skin that makes him feel like an alligator; Irais's kids are bullied because of the embarrassing growth on her head; Johnny has been living with a stubborn lump on his back for too long.

The Last Unicorn

Matt has a skin condition that causes tumors to grow all over his body; Yamileth hasn't pursued her dreams because of the lump on her neck; Pat is covered with dark spots from her neck to her abdomen; Jennifer has a unicorn bump on her forehead.

Tumor Takeover

April is covered in bumps that disfigure her arms; Genner flies all the way from the Philippines to have Dr. Lee help with his bumpy nose; Chris suffers from psoriasis that nearly covers his body and a bump on his head.

Nose No Bounds

Taylor has a large bump at the base of her spine that is far more dangerous than she realizes; John jokes about his hip lump, but it's no laughing matter; Noelle had her ears stretched as a teen, but now wants them repaired.

An American Tail

Belinda's lump on her neck causes her to basically be immobile; Nicole won't get married until she gets her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home and now needs Dr. Lee.

A Lipoma Jackpot

Diane has tumors all over her body that have ruined her life; Will fears his shoulder lump will be ripped open at work; Anthony's daughters force him to get his lump examined; a woman detests her hideous varicose veins.

The Curious Case of the Pooting Cyst

Half of Mary's body is a size 18 while the other half is a size 8; Anthony's cyst is in the area called the "Triangle of Death;" Shane wants to get a lump off his back; Brandi is anxious about getting a lump removed from her chest.

This Cyst Persists

Ronen's mysterious lump above his knee is one of the largest Dr. Lee has ever seen; Amber suffers from a debilitating skin disease that no one understands; Sandy has a neck lump she calls Tommy; Kristy's eyelid cyst is ruining her life.

The World's Largest Lump

Melissa tries to cover a huge lipoma with a sweatshirt for years; Tyler's fear of cancer keeps him from having his huge head lumps diagnosed; Tahj is covered in painful boils; Amber has ear keloids that take control of her life.

The Lipoma Whisperer

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Dr. Sandra Lee is a renowned dermatological surgeon tasked with removing life-altering growths from her patients' skin so they can try to reclaim their lives.

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At the Holiday season, cysts are a-popping, lipomas are dropping, and Dr. Lee's in good cheer; the doctor and her staff are up against a challenge with 12 pops in one day.

S1 | The 12 Pops of Christmas