I Am Legend (2007)

Robert Neville, a scientist, is a survivor of a man-made plague that transforms humans into mutants; he wanders alone through New York City, calling out for other possible survivors, and works on finding a cure for the plague using his own immune blood; Neville knows he is badly outnumbered and the odds are against him; the infected wait for him to make a mistake that will deliver Neville into their hands.