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Quinlan conceives a desperate plan; Eph wrestles with his conscience; Fet undertakes a suicide mission; Dutch and Gus prepare for battle.

The Strain

The Last Stand

An unexpected guest brings old conflicts to the surface, dividing the heroes and threatening the group's trust; with questionable new intelligence in hand, the group launches a make-or-break final assault on the Master.

The Traitor

Reeling from loss, the heroes regroup; the heroes devise a new plan to track the Master through human collaborators, beginning at the blood farm with someone Dutch knows all too well.

Extraction

With his health failing, Setrakian ignores Eph's warnings and pushes himself to the limit in his quest for victory and revenge; Fet and Quinlan race back to Manhattan, while the Master seals off the city and prepares to eliminate them all.

Ouroboros

Fet and Quinlan must figure out how to get the nuclear bomb back to New York, while a desperate Eichhorst draws near; love-struck Zack tries to learn more about his new crush, but makes a devastating discovery.

Tainted Love

Fet and Quinlan track a convoy carrying their prized nuclear weapon; Eph and Alex search for clues to uncover the Master's plan for the fate of the human race; a familiar enemy traps Dutch, who encounters an old friend as well.

Belly of the Beast

Dutch is forced to make a deal with Desai, while she plots to escape a strigoi breeding facility; Eph and Alex seek to uncover the dark secrets behind the Partnership's new plan; Gus and Creem face off against a gang encroaching on their turf.

New Horizons

Quinlan and Fet discover that stealing a nuclear warhead is not easy when they encounter an unexpected enemy; Eph and Alex concoct a new weapon to use against the strigoi; frustrated with his seclusion, Zack discovers a love interest.

One Shot

Imprisoned as a subject in a strigoi breeding program, Dutch is desperate to escape and find Setrakian; Gus recruits his cousin for the inside job that will put his gang at the top of the new world's underground economy.

The Blood Tax

Out of the ashes of humanity's nuclear war, Night Eternal has begun; Eph abandons New York for Philadelphia, where he encounters new fighters who rekindle his drive to fight back; Fet and Quinlan search for a new means of stopping the Master.

The Worm Turns

A team investigates a mysterious viral outbreak with hallmarks of an evil strain of vampirism.

S4 E1 | The Worm Turns

E10 | The Last Stand

E9 | The Traitor

E8 | Extraction

E7 | Ouroboros

E6 | Tainted Love

E5 | Belly of the Beast

E4 | New Horizons

E3 | One Shot

E2 | The Blood Tax

E1 | The Worm Turns