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Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

My 600-Lb. Life

David's Journey

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Lisa's Journey

For Larry, a second weight-loss surgery would mean a second chance at a career as a gospel recording artist.

Larry's Journey

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Dolly's Journey

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Ontreon's Journey

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

Margaret's Journey

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Lucas' Journey

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

James B's Journey

Ryan moved to Montana to keep himself from going down a dark path of drug addiction but his new path may be no less lethal than the last if he can't find a way to curb his eating habits before they kill him.

Ryan's Journey

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

Paul's Journey

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

Lacey's Journey

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

Mike's Journey

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The medical journeys of morbidly obese people are told, as the people attempt to confront lifelong emotional and physical struggles and make the courageous decision to undergo high-risk weight-loss surgery.

S10 E10 | Margaret's Journey