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While at a real estate conference in St. Louis, a man finds his wife drowned in the bathtub in their hotel room.

Forensic Files

Slippery Motives

After more than 20 people on a Native American reservation die suddenly from a flu-like disease, Navajo medicine men provide a clue that leads to a most unlikely killer.

With Every Breath

A woman who survived a deadly childhood fire sends police a letter charging that her father killed her mother 30 years ago.

Haunting Vision

A beverage company pleads guilty to violating federal safety laws when a baby dies from E. coli after drinking apple juice.

Core Evidence

A new life-insurance policy sparks suspicions of murder when a Nova Scotia schoolteacher's body is found at the bottom of her basement stairs.

Accident or Murder?

Police exhume the body of Karla Brown, murdered in her home in 1978, to study bite wounds, which eventually lead to the killer.

Body of Evidence

When a Pennsylvania man checks into a hospital for leg pain and later dies of thallium poisoning, police investigate his wife and find her in the process of collecting an insurance payment for her previous husband's death.

Til Death Do Us Part

In Lorton, Va., police attempt to determine who abducted 5-year-old Melissa Brannen after she disappears from a Christmas party, but cannot be certain until they match hair from a rabbit-fur jacket Brannen wore that day.

Innocence Lost

A husband confesses to his wife's murder, only to be found not guilty a year later when a phone tip and forensic evidence point to another.

Cement the Case

A 1995 fire razes the mansion of a Kansas doctor, killing two of her three children; disturbing accounts from an ex-husband lead investigators to believe the doctor set the blaze herself.

Ultimate Betrayal

A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.

The Killing Room

A mother claims that an intruder murdered her two sons, but lacking a motive, police use blood-spatter analysis and behavioral profiling to reconstruct a different scenario.

Invisible Intruder

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Retracing the steps of real investigations with interviews and dramatic re-creations as experts draw on forensic science to solve baffling crimes and other mysteries.

S4 E2 | The Killing Room