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Both born with brittle bone disease, Dejua and Antwon have suffered over 600 breaks between them; Robert's spine is not connected to his hips; In California, Yesi, 35, was born with diastrophic dysplasia, a rare type of dwarfism.

Body Bizarre

Broken My Bones Over 400 Times

The family of conjoined twins, Callie and Carter, must decide whether to separate them; abandoned by her birth mother and born with no arms, Deborah refuses to let her tragic early life hold her back.

A Conjoined Life

After having her leg amputated, Jillian has surgery which will allow her to use her ankle as her knee; in Peachtree City, Ga., Ashley Kurpiel suffers from a rare condition that turns her muscles to bone.

My Ankle Is My Knee

Natalia was born with a rare condition referred to as the vanishing bone disease; Sanja has a condition that causes blisters to form on her skin.

I Have Vanishing Bones

Natalie suffered major, life-changing burns after a bonfire explosion; aged 18, she's not letting her burns hold her back; in Mississippi, 11-year-old Levi has a rare form of dwarfism.

A Life Changing Accident

In Madurai, India, Ravi receives life-changing surgery to remove the huge tumors that cover his face; in California, Lauren has 24-hour treatment to prolong her life.

Facial Tumours Wont Stop Growing

Brandon's life changes forever when surgeons remove a large piece of his skull; Harper's rare condition means she makes skin 10 times faster; Rafi embarks on an incredible journey from a devastating brain hemorrhage to a successful career.

Missing Half A Skull

After 22 surgeries and losing his right eye, Amit refuses to let his incurable neurofibromatosis define him. 9-year-old Rajeshwari seeks out medical help to deal with her Ichthyosis. Mari Jade suffers from daily fits.

Tumors Forced My Eye Out

In Staten Island, New York, 15-year-old John suffers from epidermolysis bullosa and has no indication of how long he might live; in Kansas City, 28-year-old Justice suffers from a rare sleep condition called chronic neurological disorder.

The Worst Disease You've Never Heard Of

In California, conjoined twins Erika and Eva Sandoval undergo a 17-hour surgery; in Mississippi, Wells Middleton battles through his new future after losing both his hands; in Indonesia, Andriadi Putra has over 30 kilograms of tumors on his body.

Born As One Sister

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Stories of people who suffer from rare and mysterious medical conditions, sometimes so rare even the experts do not know much about them.

S8 E10 | Broken My Bones Over 400 Times