- Smiling Friends
TV-MA | Comedy/Animated
- Sarah Silverman: Someone You Love
TV-MA | Comedy/Special
- Samantha
TV-MA | Comedy
- Sarah Silverman: We Are Miracles
TV-MA | Comedy/Special
- State of the Union
TV-MA | Comedy
- Sam Jay: Salute Me or Shoot Me
TV-MA | Comedy/Special
- Skeleton Landlord
TV-MA | Comedy/Special
- Steve-O: Guilty as Charged
TV-MA | Comedy/Special
- Shining Vale
TV-MA | Comedy/Horror
- Sierra Katow: Funt
TV-MA | Comedy/Special
- Sugar and Toys
TV-MA | Comedy
- Single Long
TV-MA | Comedy
- The Shivering Truth
TV-MA | Comedy/Anthology
- The Salad Mixxxer
TV-MA | Comedy/Special
- Seth Meyers: Dad Man Walking
TV-MA | Comedy/Special
- Steve Trevino: 'Til Death
TV-MA | Comedy/Special
- School of Champions
NR | Comedy/Drama
- Spinal Destination
NR | Comedy
- Summer Shortstacular with Big City Greens
NR | Comedy/Adventure
- Spinal Tap II: The End Continues: Extras
NR | Comedy
- Sando
NR | Comedy
- Stand Up for the Pits Comedy Special with Rebecca Corry Hosted by Kayley Cuoco
NR | Comedy/Special
- Sarah Squirm: Live + in the Flesh
NR | Comedy/Special
- Send Help
NR | Comedy
- Stars of Space Jam
NR | Comedy/Animated
- Sam Tallent: Waiting for Death to Claim Us
NR | Comedy/Special
- Sinbad: Where U Been?
NR | Comedy/Documentary
- Sábados felices
NR | Comedy/Entertainment
- Señor, dame paciencia
NR | Comedy
- ¡Solo se vive dos veces!
NR | Comedy/Drama
- Spring Shorts-tacular with The Ghost and Molly McGee
NR | Comedy/Adventure
- Sitcom
NR | Comedy
- Salt & Light
NR | Comedy/Religious
- Simón dice
NR | Comedy
- Somos tú y yo
NR | Comedy/Music