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A used tissue, 12 years after the murder of a young Missouri woman, may be what cracks the case with a suspect list a mile long.

Forensic Files

Message in a Bottle

The 1960 kidnapping and murder of brewery heir Adolph Coors III leads to one of the most intense manhunts in U.S. history.

Bitter Brew

An ammunition box and fluorescent fibers reveal the betrayal that led to the murder of a millionaire's family.

Two in a Million

When a house burns to the ground and a woman's charred remains are found, investigators must determine whether it was an accident or arson.

Fired-Up

A wax bullet, white blanket and olive colored carpeting tell a lot about the murder of a young woman found in a ravine.

Blanket of Evidence

When a man dies after falling down the stairs, a witness says one thing and the evidence says another.

Step by Step

A murder in Australia baffles police, until they find a device intended to save lives is the only witness to the man's death.

Ticker Tape

DNA profiling reveals clues leading to a killer's identity 20 years later.

Fresh Heir

How the bombs were made leads investigators in Colorado to find the perpetrator.

Small Town Terror

A woman is abducted and a month later found dead, then a tip leads investigators in the right direction.

Skirting the Evidence

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When a high school athlete is killed in a hit and run accident, investigators hoped tiny paint chips and shards of plastic would lead them to the driver.

Critical Maneuver

The body of an insurance assessor is found in a river in Tampa, Fla.; a unique murder weapon and blatant clues lead the police straight to her careless killer.

Muffled Cries

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A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

S11 E24 | Water Hazard

E42 | Message in a Bottle

E41 | Bitter Brew

E40 | Two in a Million

E39 | Fired-Up

E38 | Blanket of Evidence

E37 | Step by Step

E36 | Ticker Tape

E35 | Fresh Heir

E34 | Small Town Terror

E33 | Skirting the Evidence

E32 | Critical Maneuver

E31 | Muffled Cries