- Stand by Me (1986)
R | Comedy drama
- The Skeleton Twins (2014)
R | Comedy drama/Lgbtq
- Standing Still (2005)
R | Comedy drama/Lgbtq
- Solitary Man (2010)
R | Comedy drama
- The Spectacular Now (2013)
R | Comedy drama
- Sunset (1988)
R | Comedy drama
- Stay Hungry (1976)
R | Comedy drama
- Salvation Boulevard (2011)
R | Comedy drama
- The Saddest Music in the World (2003)
R | Musical/Comedy drama
- Soul Food (1997)
R | Comedy drama
- Southland Tales (2007)
R | Comedy drama
- Saltburn (2023)
R | Comedy drama/Thriller
- The Sessions (2012)
R | Biography/Comedy drama
- Sunshine Cleaning (2008)
R | Comedy drama
- Sparrows Dance (2012)
NR | Romance/Comedy drama
- Showing Roots (2017)
NR | Comedy drama
- Steps of Faith (2014)
NR | Comedy drama
- Seeking Dolly Parton (2015)
NR | Comedy drama
- Shake Off the World
NR | Comedy drama
- Suze (2023)
NR | Comedy drama
- Stage Door (1937)
NR | Comedy drama
- So This Is Christmas (2013)
NR | Romance/Comedy drama
- Switched
NR | Comedy drama/Fantasy
- Soy un prófugo
NR | Comedy drama
- Shoplifters of the World (2021)
NR | Comedy drama/Music
- Strong Fathers, Strong Daughters (2022)
NR | Comedy drama
- Singles
NR | Comedy drama
- Six Degrees of Separation From Lilia Cuntapay
NR | Comedy drama
- Summer at Charlotte's
NR | Romance/Comedy drama
- Sam the Man
NR | Comedy drama
- Spencer's Mountain (1963)
NR | Comedy drama
- Stalag 17 (1953)
NR | Comedy drama/War