- Stand by Me (1986)
R | Comedy drama
- The Sessions (2012)
R | Biography/Comedy drama
- Sunshine Cleaning (2008)
R | Comedy drama
- The Saddest Music in the World (2003)
R | Musical/Comedy drama
- Slap Shot (1977)
R | Comedy drama
- Southland Tales (2007)
R | Comedy drama
- Snatch (2000)
R | Comedy drama
- Solitary Man (2010)
R | Comedy drama
- The Spectacular Now (2013)
R | Comedy drama
- Sweetie (1989)
R | Comedy drama
- Stay Hungry (1976)
R | Comedy drama
- Salvation Boulevard (2011)
R | Comedy drama
- Sparrows Dance (2012)
NR | Romance/Comedy drama
- Shelby
NR | Comedy drama/Holiday
- Summer at Charlotte's
NR | Romance/Comedy drama
- Sam the Man
NR | Comedy drama
- Stalag 17 (1953)
NR | Comedy drama/War
- Spitfire
NR | Comedy drama
- Strong Fathers, Strong Daughters (2022)
NR | Comedy drama
- Suze (2023)
NR | Comedy drama
- So This Is Christmas (2013)
NR | Romance/Comedy drama
- Sherlock, Jr. (1924)
NR | Comedy/Romance
- Steps of Faith (2014)
NR | Comedy drama
- Shake Off the World
NR | Comedy drama
- Seeking Dolly Parton (2015)
NR | Comedy drama
- Shadow of the Thin Man (1941)
NR | Romance/Comedy drama
- The Sandlot
NR | Comedy drama/Children