- Shortstober With Big City Greens
TV-Y | Comedy/Holiday
- The Sylvester & Tweety Mysteries
TV-Y | Comedy/Animated
- Super Duper Bunny League
TV-Y | Comedy/Action
- Sando
NR | Comedy
- Spinal Tap II: The End Continues: Extras
NR | Comedy
- Sarah Colonna: I Can't Feel My Legs
NR | Comedy/Special
- Sarah Squirm: Live + in the Flesh
NR | Comedy/Special
- Simply Marvalous
NR | Comedy/Special
- Send Help
NR | Comedy
- School of Champions
NR | Comedy/Drama
- Summer Shortstacular with Big City Greens
NR | Comedy/Adventure
- Spring Shorts-tacular with The Ghost and Molly McGee
NR | Comedy/Adventure
- Samantha Hale: Only Happy When It's Raining Men
NR | Comedy/Special
- Sitcom
NR | Comedy
- Salt & Light
NR | Comedy/Religious
- Simón dice
NR | Comedy
- Stars of Space Jam
NR | Comedy/Animated
- Sebastian Maniscalco Presents: Pat McGann -- When's Mom Gonna Be Home?
NR | Comedy/Special
- Sábados felices
NR | Comedy/Entertainment
- Señor, dame paciencia
NR | Comedy
- Sinbad: Where U Been?
NR | Comedy/Documentary
- State of the City
NR | Comedy/Special
- Suso's show
NR | Comedy/Entertainment
- ¡Solo se vive dos veces!
NR | Comedy/Drama