- Science of Stupid: Ridiculous Fails
TV-PG | Science/Comedy
- Sunday Night Cartoon All-Stars
TV-PG | Comedy/Children
- Sherri
TV-PG | Comedy
- Steven Universe
TV-PG | Comedy/Action
- Shortstv Selects Crime Stories
TV-PG | Comedy/Crime
- Svengoolie
TV-PG | Comedy/Horror
- Scooby-Doo and Guess Who?
TV-PG | Comedy/Action
- Scandinavian Stories
TV-PG | Comedy/Drama
- Sister Boniface Mysteries
TV-PG | Crime drama/Comedy
- Shortstv Selects War Stories
TV-PG | Comedy/Drama
- Stars of Space Jam
NR | Comedy/Animated
- Sposami
NR | Comedy/Miniseries
- Sinbad: Where U Been?
NR | Comedy/Documentary
- Sábados felices
NR | Comedy/Entertainment
- Suso's show
NR | Comedy/Entertainment
- Spinal Tap II: The End Continues: Extras
NR | Comedy
- Sando
NR | Comedy
- Such Is life
NR | Comedy
- Sarah Squirm: Live + in the Flesh
NR | Comedy/Special
- Send Help
NR | Comedy
- Spring Shorts-tacular with The Ghost and Molly McGee
NR | Comedy/Adventure
- Sitcom
NR | Comedy
- Salt & Light
NR | Comedy/Religious
- Somos tú y yo
NR | Comedy/Music
- Simón dice
NR | Comedy
- School of Champions
NR | Comedy/Drama
- Stand Up Trump: Making America Fun Again
NR | Comedy
- Summer Shortstacular with Big City Greens
NR | Comedy/Adventure
- ¡Solo se vive dos veces!
NR | Comedy/Drama