The movie doesn't seem to be about much of anything other than violence, and, in the end, the survivors don't seem to have been affected one way or another by all of it.
Child in almost constant peril; she falls down a flight of stairs, injuring her head. Many characters are killed in wildly gory ways. Gushing, spurting, spraying blood throughout. Character's mouth and nose glued shut; another character stabs him in the cheek so he can breathe, then the man slices open his mouth with broken glass. Burned, charred body. Woman bashed in head with hammer. Guns and shooting. Various blades and sharp objects: slashing and stabbing. Brutal fighting, punching, slamming, choking, hitting with hard, blunt objects, etc. Child stabs adult in foot with pitchfork; he slaps her, hard. Gouging eyes out. A character admits to having raped someone. A dog dies, fur matted with blood (character digs a bullet out of its corpse). Person attacked by dog. House on fire. Child holding gun. Explosion. An organ-trafficking ring is part of the plot (discussed on a TV news report). Villains treat animals poorly.
Many uses of "f--k," plus uses of "motherf----r," "bitch," "testicles."
Cigarette smoking. Indirect references to villains being meth cooks/drug dealers (not directly spoken). Child given a knockout drug in a glass of juice. Secondary characters drink what could be beers out of cans.