No real messages; this is mostly a story of bad things happening to random people. Normally in these types of movies, characters may "deserve" their fate, but that idea doesn't really apply here.
Surreal nightmare sequence; person with gory stomach wound. Characters with amputated limbs. Gory, graphic face wound. Character has seizure, bleeds from eyes. Character baits a trap with a (presumably dead) small furry animal. Knife. Blood oozing from under face bandage. Unpleasant imagery (close-up of eating runny eggs and chunks of meat). Descriptions/images of people getting sick and dying from eating "sordico." Characters tied up, imprisoned. Character caught in animal trap.
A couple has sex; woman shown on top of a man. No graphic nudity. Scene of a character (possibly?) masturbating in the shower; his hand makes jerking motions below the frame.
Uses of "f--k," "s--t," "damn," "goddamn," "butt," "shut up," "idiot," "scumsucker," "swear to f--king God," plus exclamatory use of "Jesus" and "Jesus Christ," "God."
Sunoco gas station shown.
Characters given knockout drugs with a needle.