The film is a demonstration of profound friendship. Love isn't just feeling, it's doing. The point is also made that people are more than the job or money they have. Themes include compassion, courage, gratitude, integrity, and teamwork.

Verbal hostility. Smacking and shoving. Storyline deals frankly with terminal illness and loss; characters are sad, and a woman is shown in her final stages of life: frail, in excruciating pain, and in the throes of psychosis.

Several affectionate scenes between a married couple, including showering together (nothing explicit shown). A character's dating life is a recurring topic. Kissing. Joke about phone sex.

Strong language throughout, including: "ass," "a--hole," "boobies," "dips--t," "goddamn," "nutsack," "s--t," and several uses of "f--k," including "Jesus f--king Christ."

T-shirt with a particular restaurant name on it is seen several times.

Beer is served with dinner and in social situations. Joke about someone smelling like cigarettes. Prescribed medications are shown and discussed throughout, but nothing is taken for the sake of pleasure.