Vague arguments about gun violence -- i.e., whether a gun is a tool for good or for evil, whether it depends on who's holding it, or whether it's evil in and of itself. Should a gun's maker be held responsible for the deaths of those killed with it? But these ideas aren't discussed in depth, and no answer is offered. On the other hand, the movie's biggest conflict seems to revolve around whether to accept the supernatural/unexplained as a part of life.
Gun violence, with shooting and killing. Minor blood spatter shown. A child who's possessed by a malevolent spirit fires a shotgun at a woman. Ghosts and scary stuff. Jump scares. Scar on chest.
A male character is shown in the company of three women, who may be hired prostitutes; he kisses all three as they go out the door. A woman's naked back is shown.
A use of "bitch" and "damn," and "oh my God" and "Jesus Christ" as exclamations.
Drinking, Drugs & Smoking
A main character abuses laudanum, ingesting drops every so often from a glass dropper. His supply is taken away, and the problem never returns. He also drinks from a flask, drinks whiskey at home, and covets a drink while a guest at the Winchester house. Minor characters also take laudanum.