Talks quite a bit about the way humans abuse our planet, consuming too many natural resources and leaving too much waste -- which is certainly worth discussing. But the movie takes a fairly pessimistic view, as if the problem is beyond solving.
Some blood shown during the "downsizing" process; teeth pulled. Discussion of "heads exploding" while perfecting the process. Brief altercation in a bar. Lab mice appear to be harmed during experiments. Minor characters die. Arguing. Protesting.
Brief full-frontal male nudity, seen mainly at a distance or in photographs. Naked male bottom seen briefly in shower. Kissing, suggested sex at wild party. Some strong sex-related talk.
More than one use of "f--k" (several in a row in one scene), plus "s--t," "a--hole," "bitch," "ass," "idiot," and "Jesus," "oh my God" (as exclamations) and "hate her guts."