The movie isn't out to send any positive messages and may upset those of faith; even though God and Satan exist, they're portrayed as stupid and banal and are ultimately killed.
Lindsey and Ben don't give in to the Beast's demand and stay courageous under the threat of annihilation. But their bravery is counterbalanced by the depiction of God as a cursing, bitter little man who's ultimately mortal.
It's the apocalypse, so millions die (albeit pretty bloodlessly) -- from burning rocks hailing from the sky, looting, a virus, killer wraiths, and nuclear missiles aimed at Chicago and other places. A precision laser kills even tiny targets, like a crow flying. God is killed (electrocuted) along with Satan. Jesus is also killed in a comical fashion.
Lots of vulgar sexual references: discussion of masturbation, "d--k-shaped foods," Lindsey's breasts, virginity, the way a character's vagina probably tastes, a man's penis and erection, how a first time will go, sexual positions, pubic hair trimming, and more. The Beast serenades Lindsey by singing a song about putting his penis in her vagina.
Incessant use of "f--k," "f--ker," "motherf--king," "s--t," "bitch," "a--hole," "d--k and balls," "p---y," "c--k," "screwed," "whores," "shut your mouth, "moron, and more. A father calls his son "retarded," "mongoloid," and "idiot."
Dodge Ram, Mercedes, Vin Diesel, Chronicles of Riddick, and Jimmy Neutron are all mentioned or shown.
Drinking, Drugs & Smoking
People and undead wraiths smoke lots of marijuana, and people drink, including a televangelist who wasn't raptured who turns to vodka.