At first the movie celebrates commitment-free sex and wealth achieved through exploitation, but eventually Jamie and Maggie fall in love. In order to stay together, they must learn to be true to themselves and to value empathy, tolerance, and selflessness.

Jamie occasionally slaps and smacks his annoying brother, with no real damage.

Jamie is a serial seducer who has sex with several different women -- and sometimes multiple partners. He falls in love with Maggie and has sex with her many times. Viewers see Jamie naked from head to foot (buttocks are shown, but no genitalia); Maggie is also naked several times (breasts are shown). Other minor female characters are seen in various stages of nudity. There's kissing, clothes being ripped off, suggestions of oral sex, minor thrusting, orgasmic moaning, and couples lying in bed (or on the floor) after sex. Also strong, constant sex talk, including conversations about Viagara and erections.

Very strong language, including many uses of "f--k" and "s--t," plus "c--k," "laid," "p---y," "t-ts," "ass," "a--hole," "hell," "bitch," "damn," "goddamn," "dick," "slut," "oh my God," "goddamn," and "Jesus" (as an exclamation).

Jamie works for Pfizer; many drugs are referenced by name brand -- including Zoloft, Prozac, and Viagra -- and play a huge role in the movie. Characters eat Pop Tarts for breakfast in one scene.

Prescription drugs are a huge part of the plot, but characters don't overindulge, and the main characters rarely take any drugs at all -- though Jamie tries Viagra at a party and has a comically bad reaction. A homeless man takes Prozac, and it eventually improves his life. Characters drink quite often, including wine, whiskey, and beer. After a bad day, Maggie swills a bottle of vodka in an attempt to get sloppy drunk and wash away her pain. Characters discuss having taken Ritalin as children.