Though the superficial message is Dr. Jennings facing his worst phobia and triumphing, some might detect a sub-theme: a sardonic portrayal of "peaceful" small-town USA as more treacherous, small-minded, and mean-spirited than the major metropolitan communities.
Spider bites, a few in closeup, resulting in seizures and death. A sight of hideously withered human and animal corpses. Spiders are squashed and burned; human victims include a nice old lady and a high school athlete. Climactic incendiaries and explosions, and even a projectile weapon.
No full toplessness, but female flesh as a spider in a shower crawls between a girl's exposed cleavage. Science discussion of the sex organs possessed by the species of spider involved. Suggestion that (married) humans and (unmarried) spiders are about to have sex.
"Damn," "hell," the s-word, "SOB," "God-damned."
Drinking, Drugs & Smoking
Some social drinking. A luxury wine collection in a cellar ends up being key to the climax.