The show promotes keeping an open mind when it comes to popular beliefs about the vicious nature of the fish it tracks. Each episode features many emotional accounts from injury victims and witnesses to deaths from fish-induced wounds (for example, a grandfather recounts how he only recovered the bones of his young grandson after he was attacked by piranhas).

Re-enactments of drowning scenes and blurred shots of people attacked by flesh-eating fish. The host often uses himself as bait, swimming in fish-infested waters to test their attack instincts, so there's always the possibility of injury. He also baits them with animal carcasses so he can watch them devour the meat.

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