The show's premise is based on a deception -- that the main character is psychic. But that deception is put to good use, solving crimes and bringing criminals to justice (amid lots of snarky humor). The main characters also have a strong friendship.
Each show investigates a crime. Dead bodies with some blood (usually very little) are shown, and brief violence with weapons is depicted. But this isn't a major element of the show -- it's more about getting to the bottom of the mystery.
Lots of flirting (mostly Shawn hitting on attractive women) and occasional making out. References to "sleeping together."
Not too frequent, but words include "damn," "bastard," etc.
The main character drives a Toyota -- a pretty obvious product placement. Other brands show up and are mentioned by name, including Dunkin Donuts.