Don't look for positive messages here. Although the Botwins love each other, their family relationships are constantly tested and twisted beyond most people's breaking point. Selfishness is often rewarded, and plenty of illegal activity takes place without a hint of consequence.
Somewhat sporadic depending on the season/episode, but it can be quite shocking when it happens. Stand-off scenes between drug dealers include lots of guns; Nancy participates in a drive-by; other bloody wounds appear (some from gunshots, some from other sources -- like animal attacks). Several abrupt deaths. Also some beatings and car accidents.
Infrequent full-frontal nudity and lots of partial nudity (breasts, buttocks, more). Frequent sex scenes (some fairly explicit, even for pay cable, and some involving teen characters). A character takes a young boy to a "massage parlor" as a coming-of-age treat. Sex toys show up on occasion.
Frequent and explicit; nothing is bleeped. "F--k," "s--t," "a--hole," "pu--y," etc. -- they're all there.
Few specific product names are mentioned (though Nancy does love her Diet Coke), but most of the denizens of Agrestic are very materialistic.
Drinking, Drugs & Smoking
The show's premise is closely tied to marijuana -- growing it, selling it, smoking it, baking it into pastries, etc. Later seasons expand to cover more of the illegal drug industry. Adults and teens also drink regularly, and some use drugs like cocaine.