While the main characters are humanly flawed and deal with problems like adultery and substance abuse, they're on the side of justice. The cast is multicultural; recurring female characters are generally portrayed as strong and capable. An occasional character is disabled.
Violence varies from episode to episode. FBI agents carry and sometimes use guns and engage in tense stand-offs, but blood is minimal.
Some minor sexual activity: Characters wake up in bed together, and the main characters engaged in adultery but were remorseful. Plots sometimes revolve around sexual themes, like prostitution or pornography.
Some adult language in certain episodes, but not generally noticeable.
Drinking, Drugs & Smoking
The main character was addicted to painkillers. Another recurring character may have a drug abuse problem, but drug use has serious repercussions on the show. Plots may involve drugs, but not without consequences.